Association of Perceived Social Support and Medication Doses Interruption Among Pulmonary Tuberculosis Patients in Western India: A Cross-sectional Study

Principal Investigator(s):  View help for Principal Investigator(s) Nirmal Ahuja, Pennsylvania State University-Harrisburg

Version:  View help for Version V1

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Final Complete Data Set. for Analysis.sav application/x-spss-sav 39.3 KB 09/20/2023 03:43:PM

Project Citation: 

Ahuja, Nirmal. Association of Perceived Social Support and Medication Doses Interruption Among Pulmonary Tuberculosis Patients in Western India: A Cross-sectional Study. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2023-09-20. https://doi.org/10.3886/E193946V1

Project Description

Summary:  View help for Summary Despite the ongoing global and national efforts, tuberculosis (TB) remains a major public health problem in developing countries like India. Studies in India have explored the role of social support in TB medication adherence, however, there is limited research that focuses on quantifying the association of patient’s perceived social support. This cross-sectional study aims to fill this gap and aims to examine and quantify the association between perceived social support and medication dose interruption among pulmonary TB patients in Western India. A sample of 477 participants was recruited from three directly observed treatment centers. Data on participants' medication dose interruption in the last month, their clinical characteristics, and their perceived social support were collected. Descriptive and inferential statistics were applied for analysis. Perceived social support presented a significant association with TB medication dose interruption and its frequency. Compared to those with high social support, respondents who reported low social support were significantly 2.6 times more likely to report medication dose interruption in the last month [Adjusted OR = 2.6 (95% CI: 1.556–4.403), P<0.001]. More specifically, family support was also observed to be significantly associated with medication dose interruption. Respondents who reported low family support were significantly 4.1 times more likely to miss their doses when compared with respondents who reported high family support [Adjusted OR =4.1 (95% CI: 2.482–7.070), P<0.001]. This study contributes to identifying and quantifying the association between perceived social support and medication dose interruption. It could potentially inform various policymakers, researchers, program implementation experts, and field personnel in formulating the desired intervention strategy to combat this unmet challenge of medication adherence among TB patients in India.

Scope of Project

Subject Terms:  View help for Subject Terms social support; tuberculosis; medication dose interruption; pulmonary tuberculosis; perceived social support
Geographic Coverage:  View help for Geographic Coverage Bhiwandi, Thane, India
Time Period(s):  View help for Time Period(s) 10/2018 – 11/2019
Collection Date(s):  View help for Collection Date(s) 10/2018 – 11/2019
Universe:  View help for Universe Pulmonary TB patients aged 18 and above seeking treatment at the three DOT centers (Shanti Nagar, Gayatri Nagar, and Nayi Basti) in Bhiwandi City, Thane District, Maharashtra, India.
Data Type(s):  View help for Data Type(s) survey data

Methodology

Response Rate:  View help for Response Rate A total of 586 respondents were approached to participate in the study. Out of them, 47 were ineligible and 62 participants refused to participate. There were a total of 477 completed surveys with a response rate of 81%.
Sampling:  View help for Sampling Using the existing literature which states about 50% of tuberculosis medication non-adherence prevalence rate in India, the sample size was calculated at 80% power and 0.05 level of significance. The sample size required for this study was 350 participants. Our final sample size included 477 participants.
Collection Mode(s):  View help for Collection Mode(s) on-site questionnaire
Scales:  View help for Scales 1. The socioeconomic class was identified using the 2017, Kuppuswammy Scale.
2. Depression was assessed using a validated patient health questionnaire – a two-question survey instrument.
3. Perceived social support of patients was assessed by using a 12-item Multidimensional Scale of Perceived Social Support (MSPSS).
Unit(s) of Observation:  View help for Unit(s) of Observation Individuals

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V1 [2023-09-20]

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